The Sensational Spider-Man, Vol. 2 #24 (2006)

Feral
Feral Part 2 (of 5). With not one, but two blood-thirsty Lizards stalking the streets of New York, Spidey's in deep, deep trouble. Lucky for him, the Black Cat is willing to play sidekick to her ex-boyfriend. But with Felicia Hardy exhibiting bizarrely ferocious behavior of her own, is she more of a liability than a help? And what strange transformations are coming over John Jameson and what do they have to do with MJ?
Release Date: 2006