Batman: Death and the Maidens #8 (2004)

Death and the Maidens, Chapter Eight
For centures, Ra's al Ghul has sought to fight evil in the world, and long ago concluded that the human race would have to be greatly thinned in numbers. Over his many, many years he's fathered an army of children in the hope of producing an heir worthy to follow him. Nyssa was one such child. Having suffered through the horrors of the Nazi concentration camps, she's watched her entire family die. And thanks to the same camps, she can no longer bear children. Hoping to reach her own emotions again, she's plotted two murders. She intends to assassinate the Man of Steel, as well as kill her own father.
Release Date: 2004