Ultimate Spider-Man, Vol. 1 #14 (2001)

Doctor Octopus
Peter's class is given a project: in one week, they will come in as a superhero, and describe why they do what they do. While discussing this project, they meet Gwen Stacy, who just came to the school for her first day. Meanwhile, Doctor Otto Octavius wakes up in government custody. He learns that his mechanical arms were found grafted to him, but rather than remove them, government scientists left them attached to see what would happen. He doesn't take the news well.
Release Date: 2001