The Demon, Vol. 1 #12

Rebirth of Evil!
“REBIRTH OF EVIL!” Long ago in the Dark Ages, the Demon investigated the strange rumors of Castle Rakenstein and uncovered a sinister laboratory filled with monstrous creations. Without hesitation, Etrigan put an end to the horrific experiments of the castle's master. Etrigan believed the nightmare ended there. He was wrong.
Release Date: 1973