The Amazing Spider-Man, Vol. 2 #24 (2000)

Maximum Security - The Distinguished Gentleman From New York, Part 3: Failure Is Not An Option
Peter and the Ranger join forces to track down Arthur Stacy and save him from Stewart Ward. It's tough going, but if they can find them in time, they might just be able to find and distribute and antidote to the pathogen that's already been released on the popultion.
Release Date: 2000