New Avengers, Vol. 1 #31 (2007)

The Initiative - Revolution, Part Five
The New Avengers are battling for their very lives against the Hand. In fact, Dr. Strange has already been seriously wounded. As the Avengers fight wave upon wave of ninjas, they struggle to undo whatever has taken hold of Echo, causing her to turn on her teammates. But when she is freed from the Hand's compulsion, her actions reveal that the current situation is even more sinister than it initially appeared.
Release Date: 2007